Hayao Miyazaki and Hideaki Anno have worked together on a few different projects – Anno even provides the voice of Jirō Horikoshi in Miyazaki's The Wind Rises – but their working relationship began with Nausicaä. Anno animated The God Warrior for that film and Miyazaki was clearly very pleased with his work.
Hideaki Anno then went on to make one of the most influential anime series of all time, Neon Genesis Evangelion, and Miyazaki became one of the most highly regarded animation directors working today. If not the most highly regarded. They're a hell of a animation power couple
Anime News Network are reporting today that Miyazaki mentioned on Ō-sama no Brunch, a TV programme he was appearing on to promote The Wind Rises, that Anno is very keen on the idea of making a sequel to Nausicaä and that Miyazaki is happy for him to do it.
When asked about making a second film Miyazaki replied,
No, I don't. I don't really feel like doing it, but Anno keeps on saying, 'I want to do it! I want to do it!,' so I tell him now that I've come to think lately that if he wanted to do it, it would be fine for him to do it.
It obviously doesn't sound anything like a done deal but Miyazaki certainly seems to suggest that Anno is very keen on the idea. Unfortunately I can't speak Japanese so I'm relying on ANN's translation of the interview but I highly doubt that they would get this one wrong.
I've embedded the video below though so if any Little Bleeders speak Japanese they can help confirm that it is indeed correct.