Taken by Danimal at Big Wow in San Jose, here's a photo of Art Adams' upcoming Original Sin spread that appears to feature… Well, the Marvel Universe.
Being drawn on several boards, it does have the look of something that might need… Folding out…
You can hear Art Adams and Mark Brooks talking about if right here.
UPDATE: Ron Hansen writes to add,
The bottom middle and bottom left panels have already appeared as the variant covers on #1 and #2 respectively. If this pattern holds, it means they're working their way round it clockwise and will finish with the bottom right panel – which, significantly, was mostly blank in the video clip and so presumably might contain spoilers. The other possibly interesting thing is that this looks like a nine artboard grid. ORIGINAL SIN is an eight issue series. This would mean either the third or seventh issue might have a fold-out or front'n'rear cover.