Double Fine and Bandai Namco's RAD is a 3D action rogue-like game set in a post-apocalyptic world where humanity has faced it's doom twice over sometime in the mid-1980s. So everything is neon. Players take on the role of a teenage protagonist who ventures into the Fallow, which is a constantly changing radioactive wasteland filled with mutated creatures.
The fun part about RAD is that, the deeper a player gets into the Fallow, the more they change due to radiation exposure. However, because this is a video game, those mutations are pretty helpful and end up giving you super powers which you can use to defeat bosses and continue journeying about in the nuclear wastes.
Like many rogue-like games, you can die incredibly easily in RAD, and a death means you have to start over. However, you can deposit some of your tapes (which are used as currency), which will allow you to buy better gear and weapons on your next runs.
Each time you die and restart, you'll get a different starting mutation, which will keep the gameplay from getting stale with all the inevitable resets you'll be doing.
When you do manage to complete the game, there are a handful of endings you can unlock, so it's definitely worth replaying a few times if you can stomach all the extra radiation.
RAD is available now on PC via Steam.