In the comics, Daisy Johnson aka Quake goes on to become the Director of SHIELD. With her being a main character on the television series, EW.com asked executive producer Jed Whedon if the same thing is possible with Chloe Bennett's character?
We've hinted at it a bit, that Coulson thinks she can play more of a leadership role. We'll see how it goes, and where the story takes her. She's been through a lot so that usually turns someone from a rookie into a seasoned veteran, which is what you need to lead. We'll see if she steps up to the plate.
And they've already established the idea that an Inhuman can be Director, with the fact that Jeffrey Mace is one. Not sure if that dynamic would work for a while on the series though. Daisy hasn't lead a team enough yet to start running the whole thing.