It wasn't exactly a sure thing, but now it appears it is. Sony has announced Marc Webb will indeed return to direct The Amazing Spider-Man 3, to close off what he has called the "trilogy."
But Sony has no plans to stop there. There's already Amazing Spider-Man 4 announced (though it may not have Webb or star Andrew Garfield, at this point) and of course Venom, to be directed by Alex Kurtzman and Sinister Six, which will be in the hands of Drew Goddard.
Sony chief Amy Pascal reckons that translates into an endless stream of Spider-Man movies to rival Marvel's output:
We are expanding the 'Spider-Man' universe into 'The Sinister Six' and 'Venom,' so that we have 'Spider-Man' movies every year.
The Amazing Spider-Man 2, which appears to set into motion the subsequent sequels and spin-offs, releases on May 2nd.