I almost forgot about the movie I Am Legend. Based on the Richard Matheson 1954 novel of the same name, it's actually the third time it was adapted. The first was in 1964 starring Vincent Price and called The Last Man On Earth and then there was the 1971 version starring Charlton Heston called The Omega Man. The 2007 Will Smith version did pretty well, grossing $585 million worldwide.
Now the guys at Cinema Sins have gotten a hold of it for their Everything Wrong With… series.